- PII
- 10.31857/S0026365624030144-1
- DOI
- 10.31857/S0026365624030144
- Publication type
- Status
- Published
- Authors
- Volume/ Edition
- Volume 93 / Issue number 3
- Pages
- 362-367
- Abstract
- Recently acquired data suggest that many infections are associated with formation of multispecies biofilms, in which both antibiotic sensitivity and the permeability of the extracellular matrix differ from those of monocultures. In this work, we show that addition of cell-free culture liquid of Staphylococcus aureus to the biofilms of Klebsiella pneumoniae and Pseudomonas aeruginosa increased the content of α- and β-polysaccharides in the matrix up to twofold, which in turn probably affected the biofilm structure. Increased content of the polysaccharide component was also confirmed by a significantly increased expression of the K. pneumoniae pgaA gene and of the P. aeruginosa pelA and pslA genes in the presence of S. aureus culture liquid.
- Keywords
- бактериальные биопленки Staphylococcus aureus Klebsiella pneumoniae Pseudomonas aeruginosa внеклеточный матрикс биохимический состав экспрессия генов
- Date of publication
- 15.05.2024
- Year of publication
- 2024
- Number of purchasers
- 0
- Views
- 34
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