RAS BiologyМикробиология Microbiology

  • ISSN (Print) 0026-3656
  • ISSN (Online) 3034-5464

Induction of alcohol dehydrogenase in Yarrowia lipolytica yeast under stress conditions

PII
10.31857/S0026365624060182-1
DOI
10.31857/S0026365624060182
Publication type
Status
Published
Authors
Volume/ Edition
Volume 93 / Issue number 6
Pages
884-888
Abstract
It has been shown for the first time that under stress conditions, the yeast Yarrowia lipolytica exhibits activity of alcohol dehydrogenase along with antioxidant enzymes. During growth on glucose, during the transition of yeast from the exponential to the stationary growth phase, caused by glucose depletion, the ability of cells to oxidize ethanol was detected. Under conditions of oxidative and thermal stress, the induction of alcohol dehydrogenase is associated with an increase in the activity of antioxidant enzymes, in particular, catalase, superoxide dismutase, glucose-6-phosphate dehydrogenase and glutathione reductase. A decrease in the intracellular level of ATP and cAMP in Y. lipolytica under various stress conditions was shown, which correlates with an increase in the activity of antioxidant systems and NAD+-dependent alcohol dehydrogenase.
Keywords
алкогольдегидрогеназа дрожжи стресс биосинтез
Date of publication
15.11.2024
Year of publication
2024
Number of purchasers
0
Views
33

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